1.基金项目
(1) 山西省基础研究计划(自由探索类)面上项目,No. 202103021224052,抗癌天然产物巴西苏木素及其类似物的合成及抗癌构效关系研究,主持,2022-2024
(2) 国家自然基金青年基金,No. 21602088,生物碱Myrrhine、Alkaloid(-)-205B及其类似物的全合成研究,主持,2017-2019
(3) 国家自然基金地区基金,No. 21362012,二环[3,3,1]壬烷-1,3,5-三酮的合成研究及其在天然产物Garsubellin A 的全合成中的应用,主持,2014-2017
(4) 江西省科技计划项目,No. 20151BBG70028,丹参天然提取物——丹酚酸 A 的化学合成及开发应用,主持,2015-2016
(5) 江西省科技支撑计划项目,No. 20142BBE50006,抗乙肝病毒药物恩替卡韦的工艺路线设计与合成,主持,2014-2016
(6) 江西省教育厅科技项目,No. GJJ14579,抗疟活性天然产物Aculeatin A,B,D,6-epi-D的不对称全合成研究,主持,2014-2015
2.代表性论文
(1) Jiangtao Liu, Xue Han, Liuping Yu, Jiandong Zhang, Shuangping Huang(*), Xihua Yang(*), Honghong Chang(*), Chemoenzymatic formal synthesis of (+)-brazilin. Nat. Prod. Res. 2024, 1-11.
(2) Shuangping Huang, Jing Ma, Yikun Yi, Mingtao Li, Ping Cai(*), Na Wu(*). Synthesis of orthogonal push–pull chromophores via click reaction of arylynamines. Org. Biomol. Chem. 2022, 20, 4081-4085.
(3) Dongdong Xu, Jiangtao Liu, Xue Han, Shuangping Huang(*), Xihua Yang(*). A novel total synthesis of (t)-brazilin. Synthetic. Commun.2022, 52, 724-732.
(4) Xiaofeng Guo, Zhiwei Xue, Dongdong Xu, Qidong Tu, Honghong Chang(*), Xihua Yang(*), Shuangping Huang(*),Total synthesis of (-)-brazilane via a lipase-catalyzed desymmetrization reaction. Nat. Prod. Res. 2021, 5125-5133.
(5) Yiying Pang, HeshengXiao, WentaoOu, XuesongZhang, XiaojiWang(*), ShuangpingHuang(*). A concise total synthesis of ()-γ-lycorane via an aromatic C-H alkylation of unactivated secondary alkyl iodide. Tetrahedron Lett. 2020, 61, 151733.
(6) ShuangpingHuang(#), WentaoOu(#), WangLi, HeshengXiao, YiyingPang, YiZhou, XiaojiWang, XihuaYang, LipingWang. A total synthesis of (+)-brazilin. Tetrahedron Lett. 2020, 61, 152052.
(7) Xiaoji Wang, Yi Zhou, Hesheng Xiao, Wentao Ou, Yiying Pang, Wang Li, Liping Wang*, Shuangping Huang*. Formal Synthesis of (±)-Aplykurodinone-1 Based on the Indium-Catalyzed Conia-ene Reaction. Synlett. 2020, 31, 1404-1408.
(8) Jiwu Wang, Wang Li, Lixia Liu, Bo Wang, Yi Zhou, Shuangping Huang(*), Xiaoji Wang(*), A unified and straightforward total synthesis of (+)-porantheridine and (-)- 6-epi-porantheridine,Org. Chem. Front. 2019, 6, 1599-1602.
(9) Ying Peng(#), Yongli Sun(#), Bo Wang, Yi Zhou, Shuangping Huang(*), Xiaoji Wang(*),Formal synthesis of (±)-aplykurodinone-1 through an intramolecular Michael addition,Tetrahedron Lett. 2019, 60, 839-842.
(10) Lixia Liu, Yongli Sun, Jiwu Wang, Wentao Ou, Xiaoji Wang(*), Shuangping Huang(*), A New Formal Synthetic Route to Entecavir, Synlett. 2019, 30, 748-752.
(11) Bo Wang, Liping Wang, Ying Peng, Yiying Pang, Hesheng Xiao, Xiaoji Wang(*), Shuangping Huang(*), Molecules, 2019, 24, 999.
(12) Xiaotong Li, Gaopeng Wang, Zhibin Zhang, Na Wu, Qianqian Yang, Shuangping Huang(*), and Xiaoji Wang(*). A concise and straightforward approach to total synthesis of (+)-Strictifolione and formal synthesis of Cryptofolione via a unified strategy. Synthetic Commun. 2019, 8, 1031-1039.
3.授权专利
(1) 王晓季,黄飞飞,黄双平,刘东旺,王高鹏,王李平,覃双林,一种合成Tarchonanthuslactone异构体的方法,中国专利:ZL 201410675605.0。
(2) 黄双平,覃双林,王晓季,林爽杰,冷晓,孙猛,张志滨,天然产物(+)-生物素的全合成方法,中国专利:ZL 201510386277.7。
(3) 王晓季,黄双平,唐琳钧,陈世鹏,王李平,吕常山,李玉萍,一种合成天然产物Jaspine 异构体的方法,中国专利:ZL 201310568119.4。
(4) 黄双平,张建廷,竹承林,王李平,王晓季,Ieodomycin A和B立体选择性合成方法,中国专利:ZL 201310661259.6。
(5) 王晓季,刘东旺,陈曦,吕常山,张建廷,陈世鹏,冯俊敏,唐琳钧,黄双平,中国专利:1,2,3-O-三乙酰基-5-脱氧-D-呋喃核糖的合成方法,ZL 201110314660.3。